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Symptomatic ileal nodular lesion: a persisting diagnostic challenge
Andrea Saibanti1,2, Marcello Di Martino1,2, Nico Pagano1,3
1Department of Health Sciences, University of Eastern Piedmont, Novara, Italy.
BMJ Case Reports
|October 28, 2025
Summary
A young male with an ileal nodular lesion was diagnosed with gastric heterotopia in a Meckel's diverticulum. This case highlights diagnostic challenges and the need for multidisciplinary care for ileal lesions.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Diagnostic Imaging
Background:
- Ileal nodular lesions present diagnostic challenges due to similar clinical presentations of benign and malignant conditions.
- Meckel's diverticulum is a common congenital anomaly that can manifest with various complications, including heterotopic tissue.
Purpose of the Study:
- To detail the diagnostic and therapeutic management of a young male with an ileal nodular lesion.
- To emphasize the importance of advanced diagnostics and a multidisciplinary approach in managing ileal lesions of uncertain etiology.
Main Methods:
- Case report detailing clinical presentation, diagnostic workup (imaging, biopsy), and surgical intervention.
- Histopathological examination of the resected specimen for definitive diagnosis.
Main Results:
- The ileal nodular lesion was diagnosed as gastric heterotopia within a Meckel's diverticulum.
- Successful surgical resection and management of the condition were achieved.
Conclusions:
- Gastric heterotopia in a Meckel's diverticulum can mimic other ileal pathologies, necessitating a thorough diagnostic evaluation.
- A multidisciplinary team approach integrating clinical, radiological, and pathological expertise is crucial for accurate diagnosis and effective treatment of complex ileal lesions.
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