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Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

31
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
31

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Updated: May 5, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
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Sensors in Multiple Sclerosis.

Angeliki G Filippatou1, Ellen M Mowry2

  • 1Division of Neuroimmunology and Neurological Infections, Department of Neurology, Johns Hopkins University School of Medicine, 600 N. Wolfe St, Baltimore, MD, 21287, USA. afilipp5@jhmi.edu.

Current Neurology and Neuroscience Reports
|October 29, 2025
PubMed
Summary
This summary is machine-generated.

Biosensors and digital tools offer advanced monitoring for multiple sclerosis (MS) patients. These technologies capture subtle functional changes, enabling personalized care and timely clinical decisions for better MS management.

Keywords:
BiosensorsDigital biomarkersDigital toolsMultiple sclerosisWearables

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Area of Science:

  • Neurology
  • Biomedical Engineering
  • Digital Health

Background:

  • Multiple Sclerosis (MS) monitoring traditionally relies on methods that may miss subtle functional declines.
  • There is a growing need for precise, continuous assessment of functional status in MS.
  • Digital tools and biosensors present an opportunity to enhance MS care.

Purpose of the Study:

  • To review current and emerging applications of biosensors for monitoring function in individuals with MS.
  • To explore how biosensors and digital tools can support data-driven clinical decisions in MS.
  • To assess the potential of these technologies in transforming MS care.

Main Methods:

  • Review of current and emerging biosensor applications in MS.
  • Analysis of biosensor capabilities in tracking diverse physiological and kinetic metrics.
  • Examination of digital health technologies for MS patient monitoring.

Main Results:

  • Biosensors effectively track physical activity, circadian rhythmicity, gait, balance, fine motor function, and bladder control in MS.
  • Novel technologies reliably detect subtle functional abnormalities often missed by conventional assessments.
  • Digital health technologies show promise for precise, continuous monitoring of MS progression.

Conclusions:

  • Biosensors and digital tools can significantly enhance the monitoring of individuals with MS.
  • These technologies facilitate personalized management by enabling tailored interventions based on unique disease trajectories.
  • Further validation and integration studies are crucial for the clinical adoption of these tools in MS care and trials.