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Updated: Jan 13, 2026

Murine Fetal Echocardiography
Published on: February 15, 2013
Fetal Speckle Tracking Technology for Critical Aortic Stenosis: Advancing Through Innovation
Julia Murlewska1, Sławomir Witkowski1,2, Iwona Strzelecka1,3
1Department of Prenatal Cardiology, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.
None:
Background and Clinical Significance: This article explores the application of fetal speckle tracking technology in evaluating critical aortic stenosis (AS) in fetuses, highlighting its potential for predicting neonatal outcomes. Case Presentation: We present two cases of fetuses diagnosed with critical AS and associated complications at late gestation. Case 1 demonstrated preserved left ventricular function, as indicated by favorable global strain (GS), fractional area change (FAC), and ejection fraction (EF) values, despite critical conditions. This infant underwent successful postnatal interventions and was discharged after an extended NICU stay. In contrast, Case 2 exhibited severely compromised left ventricular function with significantly reduced GS, FAC, and EF parameters, leading to a tragic outcome despite intensive management. Conclusions: Our findings suggest that innovative echocardiographic parameters such as GS, FAC, and EF for the left ventricle are crucial in prognostic evaluations for fetuses with critical AS. The study underscores the importance of advancements in fetal cardiology and the need for further research to enhance prognostic assessments and improve clinical outcomes in affected neonates.
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