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Related Experiment Video

Updated: Jan 13, 2026

Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library

Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library

Published on: September 30, 2019

Fibroblast Growth Factor-Derived Peptides: Sources, Functions, and Applications.

Cheng-Kun Cao¹, Zhong-Yuan Shi¹, Chuan-Bang Chen²

¹School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325000, China.

Bioengineering (Basel, Switzerland)

|October 29, 2025

Summary

This summary is machine-generated.

Fibroblast growth factors (FGFs) and their derived peptides are vital for tissue repair and metabolic regulation. This review explores FGF-derived peptides

Keywords:

clinical application fibroblast growth factor-derived peptides function

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Published on: December 10, 2010

Area of Science:

Biochemistry and Molecular Biology
Regenerative Medicine
Pharmacology

Background:

Fibroblast growth factors (FGFs) are key regulators of fundamental biological processes like development, metabolism, and healing.
FGF-derived peptides, engineered or extracted, mimic FGF functions, showing therapeutic promise.
These peptides offer potential applications across diverse medical fields.

Purpose of the Study:

To comprehensively review the origins and biological activities of FGF-derived peptides.
To elucidate the molecular mechanisms underlying their therapeutic effects.
To explore the future applications and clinical translation of FGF-derived peptides.

Main Methods:

Literature review of existing research on FGF-derived peptides.
Analysis of studies detailing peptide sources and functional characterization.
Synthesis of information on molecular mechanisms and application potential.

Main Results:

FGF-derived peptides are sourced from natural fragments or designed structures.
They exhibit diverse bioactivities, including tissue regeneration, metabolic control, and neural repair.
Potential applications span oncology, metabolic disorders, and drug delivery systems.

Conclusions:

FGF-derived peptides represent a promising class of therapeutic agents.
Further research into structural optimization and drug delivery is warranted.
Clinical translation holds significant potential for various diseases.