Gait and Postural Control Deficits in Diabetic Patients with Peripheral Neuropathy Compared to Healthy Controls

Area of Science:

• Neurology
• Diabetology
• Biomechanics

Background:

• Diabetic peripheral neuropathy (DPN) is a common complication of type 2 diabetes.
• DPN significantly impacts gait and balance, elevating fall risk in affected individuals.

Purpose of the Study:

• To investigate gait characteristics and postural control in individuals with DPN.
• To compare DPN patients with age- and gender-matched healthy controls.

Main Methods:

• Gait analysis using motion capture and force platforms.
• Static balance assessment via tandem stance tests (eyes open/closed).
• Mobility evaluation using the Timed-Up-and-Go (TUG) test.

Main Results:

• No significant differences in dynamic mediolateral (ML) center-of-pressure (COP) during walking.
• DPN patients exhibited slower gait speed, shorter steps, and poorer static balance.
• DPN patients demonstrated slower TUG performance compared to controls.

Conclusions:

• DPN patients have preserved dynamic postural control but exhibit gait adaptations and static balance deficits.
• Routine fall risk screening in DPN is recommended using static balance and mobility tests.
• Comprehensive balance assessment is crucial for managing DPN patients.