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Updated: Jan 13, 2026

06:48
Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium
Published on: August 7, 2015
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Surgical Approaches to Retinal Gene Therapy: 2025 Update
Milin J Patel1,2, Sohum Sheth3, Jessica Mar1
1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Bioengineering (Basel, Switzerland)
|October 29, 2025
Abstract
None:
Gene therapy offers a promising new frontier in the treatment of inherited and acquired retinal disease. This review describes the current surgical delivery approaches for gene therapy to the retina-subretinal, suprachoroidal, and intravitreal-and provides an update on the state of the art for each method in 2025.
Keywords:
age-related macular degenerationgene therapyinherited retinal diseaseintravitrealretinasubretinalsuprachoroidal
