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DiabCompSepsAI: Integrated AI Model for Early Detection and Prediction of Postoperative Complications in Diabetic
Sri Harsha Boppana1, Sachin Sravan Kumar Komati2, Raja Hamsa Chitturi3
1Department of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USA.
Journal of Clinical Medicine
|October 29, 2025
Summary
A Random Forest Classifier accurately predicts postoperative wound infections and sepsis in diabetic patients, achieving over 94% accuracy. This machine learning approach enables early intervention to improve patient outcomes and reduce healthcare costs.
Area of Science:
- Medical Informatics
- Machine Learning in Healthcare
- Surgical Outcomes Research
Background:
- Diabetic patients face higher risks of postoperative complications like wound infections and sepsis.
- These complications lead to extended hospital stays and increased morbidity.
- Traditional risk assessments may not fully capture the complexity of these risks.
Purpose of the Study:
- To evaluate the predictive accuracy of a Random Forest Classifier for postoperative wound infections and sepsis in diabetic patients.
- To enable early clinical interventions through improved risk stratification.
- To leverage ensemble learning for enhanced predictive performance.
Main Methods:
- Retrospective analysis of the National Surgical Quality Improvement Program (NSQIP) database.
- Utilized demographic, clinical, and surgical variables, with one-hot encoding and normalization.
- Employed an 80/20 train-test split for a Random Forest Classifier model.
Main Results:
- Random Forest model achieved >94% accuracy for both wound infection and sepsis prediction.
- Precision and recall metrics exceeded 94%, demonstrating high true positive identification.
- AUC values of 0.92 (wound infection) and 0.95 (sepsis) indicate strong discriminative power.
Conclusions:
- The Random Forest Classifier effectively predicts postoperative complications in diabetic patients.
- High performance metrics suggest potential for real-time clinical risk stratification.
- Clinical integration could improve patient outcomes and reduce healthcare expenditures.
