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Ultrasound-Guided Localization of the Refill Port for Intrathecal Infusion Pump Recharge: A Systematic Review
Beatriz Lechuga Carrasco1, Nicolás Cordero Tous1, Andrés Reinoso-Cobo2
1Virgen de las Nieves, University Hospital, 18014 Granada, Spain.
Journal of Clinical Medicine
|October 29, 2025
Summary
Ultrasound guidance for intrathecal infusion pump refills shows promise, especially in difficult cases. While not definitively proven to improve pain or satisfaction, observed benefits suggest potential advantages over traditional methods.
Area of Science:
- Medical Imaging
- Pain Management
- Neurosurgery
Background:
- Intrathecal infusion pumps are vital for managing intractable pain.
- Traditional methods for locating pump refill ports can be challenging.
- Ultrasound offers a potential improvement for refill port identification.
Purpose of the Study:
- To systematically review current knowledge on ultrasound-guided intrathecal infusion pump refill port location.
- To update existing evidence on this emerging technique.
Main Methods:
- Systematic review adhering to PRISMA protocol.
- Registered with PROSPERO (CRD 42024595671).
Main Results:
- Ultrasound guidance is predominantly used in complex cases with difficult access.
- Pain assessment, patient satisfaction, and refill time are key considerations for method selection.
- Improvements in these factors are noted in specific scenarios.
Conclusions:
- Conclusive data on pain reduction, patient satisfaction, and time efficiency are lacking.
- Notable improvements are observed in certain situations, warranting further investigation.

