Related Experiment Video

Updated: Jan 13, 2026

Cultivate Primary Nasal Epithelial Cells from Children and Reprogram into Induced Pluripotent Stem Cells
12:08

Cultivate Primary Nasal Epithelial Cells from Children and Reprogram into Induced Pluripotent Stem Cells

Published on: March 10, 2016

11.7K

The Role of IOS in Identification of Specific Treatable Traits in Pediatric Asthma: Current Limitations and Future

Joanna Połomska1, Hanna Sikorska-Szaflik1, Barbara Sozańska1

  • 1Department and Clinic of Paediatrics, Allergology and Cardiology, Wroclaw Medical University, Ul. Chałubińskiego 2a, 50-368 Wrocław, Poland.

Journal of Clinical Medicine
|October 29, 2025
PubMed

Insights

Impulse oscillometry (IOS) can assess lung function in children with asthma. More research is needed to confirm its role in identifying small airway disease (SAD) for personalized asthma treatment.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Physiology

Background:

  • Asthma management in children focuses on symptom control, lung function preservation, and maintaining daily activities.
  • Impulse oscillometry (IOS) is a non-invasive lung function test suitable for pediatric populations.

Purpose of the Study:

  • To explore the utility of IOS in early identification of small airway disease (SAD) in pediatric asthma.
  • To assess the potential of IOS for personalized asthma treatment strategies.
  • To determine the need for population-specific reference values for IOS in children.

Main Methods:

  • Literature review and synthesis of current research on IOS in pediatric asthma.
  • Discussion of the potential role of IOS in identifying SAD.
  • Analysis of the need for reference values and combination with spirometry and FeNO.

Main Results:

  • IOS shows promise for evaluating lung function in pediatric asthma.
  • Further research is required to establish IOS's role in SAD detection.
  • Population-specific reference values are necessary for routine clinical use.

Conclusions:

  • IOS may offer a valuable tool for assessing SAD in pediatric asthma.
  • Integration into clinical practice requires establishing reference values and further validation.
  • Future guidelines may incorporate IOS for SAD assessment in children with asthma.

Keywords:
diagnostic advancesoscillometrypediatric asthmasmall airway diseasetreatable traits

More Related Videos

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.4K
Asthma Detection Research Based on Voice Signal Processing and Machine Learning04:04

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

Published on: July 22, 2025

914

Related Concept Videos

Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.1K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.2K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.1K
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.4K
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
3.7K
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.2K