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Prescribing LAIs: from completing the first injection to going steady
Andrew Cutler1,2, Meghan Grady2, Alison Holladay
1Department of Psychiatry, https://ror.org/040kfrw16SUNY Upstate Medical University, Syracuse, NY, USA.
Abstract:
Non-adherence and even partial adherence to antipsychotic treatment can increase the risk of relapse in patients with schizophrenia. One strategy to improve adherence is through the use of long-acting injectable (LAI) antipsychotics. Multiple LAI antipsychotic options are available, which differ in terms of their formulation, administration, initiation, and maintenance dosing schedule. This article provides a practical guide to the conversion from oral to LAI antipsychotic treatment for the available LAI formulations as well as evidence-based principles for maintenance treatment.
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