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Implementation of Rapid Human Immunodeficiency Virus Screening Program in an Emergency Department
Caitlin C Bettger1, Brooke A Lajeunesse2, Miguel A Arroyo Cazurro3
1Infectious Disease Service, Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, United States.
Military Medicine
|October 29, 2025
Summary
Implementing rapid Human Immunodeficiency Virus (HIV) testing in the Emergency Department (ED) significantly increased HIV screening for patients with sexually transmitted infections (STIs). Despite this improvement, overall HIV screening rates in the ED remained low, highlighting the need for further interventions.
Area of Science:
- Public Health
- Infectious Diseases
- Emergency Medicine
Background:
- National guidelines recommend Human Immunodeficiency Virus (HIV) screening for all patients evaluated for sexually transmitted infections (STIs).
- Compliance with HIV screening in the Emergency Department (ED) was suboptimal due to logistical challenges and delayed test results.
- Rapid HIV testing was introduced as a quality improvement initiative to address these issues.
Purpose of the Study:
- To evaluate the impact of implementing rapid HIV testing in the ED on HIV screening rates among patients presenting with STIs.
- To assess the change in HIV screening compliance following the introduction of rapid testing.
Main Methods:
- A pre- and post-intervention study design was used, collecting data over 3 months before and 3 months after implementation.
- Rapid HIV testing was introduced for patients undergoing Neisseria gonorrhea and Chlamydia trachomatis (GC/CT) testing in the ED.
- Demographic, clinical, and laboratory data were collected via chart review to assess HIV screening practices.
Main Results:
- HIV screening increased significantly from 4.3% pre-intervention to 19.8% post-intervention (P=.001).
- Rates of bacterial STIs and empiric treatment for GC/CT remained similar between the two periods.
- HIV screening rates at primary care follow-up remained low in both periods (6.2% vs. 8.4%).
Conclusions:
- Rapid HIV testing in the ED led to a nearly 5-fold increase in HIV screening for patients with STIs.
- Despite the intervention's success, overall ED HIV screening rates remain low.
- Further research is needed to address barriers to HIV screening during primary care follow-up.

