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Ewing Sarcoma of the Mandible in an Adult: A Rare Case With Distinctive Radiologic Features
Hamid Bashiri1, Maryam Mohebiniya2
1Department of Oral and Maxillofacial Surgery, School of Dentistry Arak University of Medical Sciences Arak Iran.
Clinical Case Reports
|October 29, 2025
Summary
Ewing sarcoma, a rare aggressive bone cancer, can affect the jaw in adults. Early diagnosis and multimodal treatment are crucial for better outcomes.
Area of Science:
- Oncology
- Surgical Pathology
- Radiotherapy
Background:
- Ewing sarcoma (ES) is a rare and aggressive malignant bone tumor.
- Jaw involvement by ES is particularly uncommon, especially in adult patients.
Purpose of the Study:
- To report a rare case of Ewing sarcoma affecting the jaw in an adult.
- To emphasize the significance of prompt diagnosis and treatment for this condition.
Main Methods:
- Case report presentation.
- Review of clinical presentation, diagnostic procedures, and treatment course.
- Multimodal therapy including chemotherapy, radiotherapy, and surgical resection.
Main Results:
- Successful management of a rare adult jaw Ewing sarcoma case.
- Demonstration of the efficacy of a combined therapeutic approach.
Conclusions:
- Ewing sarcoma of the jaw, though rare in adults, requires high clinical suspicion.
- Timely multimodal therapy is essential for improving prognosis and effective management of jaw Ewing sarcoma.

