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Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow
Published on: December 15, 2023
Feasibility of Portable Laser Doppler Flowmeter for Foot Blood Flow Assessment in Patients With Chronic Limb
Masahiro Tezuka1, Shotaro Hirota1, Masashi Kawamura1
1Department of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Tochigi, Japan.
Insights
Portable laser Doppler flowmetry (LDF) effectively identifies chronic limb-threatening ischemia (CLTI) by measuring plantar blood flow. This non-invasive technique also accurately assesses the success of revascularization procedures in CLTI patients.
Area of Science:
- Vascular Surgery
- Medical Devices
- Diagnostic Technologies
Background:
- Chronic limb-threatening ischemia (CLTI) requires accurate assessment of lower extremity blood flow.
- Non-invasive methods are crucial for bedside evaluation of peripheral arterial disease.
- Laser Doppler flowmetry (LDF) offers a portable solution for blood flow measurement.
Purpose of the Study:
- To evaluate the capability of portable laser Doppler flowmetry (LDF) in identifying CLTI.
- To assess the utility of LDF in determining the efficacy of revascularization in CLTI patients.
- To compare LDF measurements with skin perfusion pressure (SPP).
Main Methods:
- A prospective study involving patients with and without CLTI.
- Blood flow measurement in dorsal and plantar areas using a portable LDF device.
- Comparison of LDF and SPP before and after surgical bypass in CLTI limbs.
Main Results:
- Plantar blood flow was significantly lower in the CLTI group compared to the non-lower extremity arterial disease (LEAD) group (p < .001).
- Post-operative plantar blood flow significantly improved after surgical bypass (p < .001).
- LDF measurements showed significant correlation with SPP changes post-revascularization (p = .023).
Conclusions:
- Portable LDF is a valuable tool for identifying CLTI.
- Plantar LDF measurements can effectively evaluate the success of revascularization.
- LDF provides a practical, non-invasive method for bedside assessment in CLTI management.
Objective:
The portable, non-invasive laser Doppler flowmeter (LDF) provides a practical alternative, enabling bedside blood flow assessment for chronic limb threatening ischaemia (CLTI). The present study aimed to evaluate whether LDF could identify CLTI and to assess the utility of LDF in determining the efficacy of revascularisation.
Methods:
The study enrolled 50 patients with non-lower extremity arterial disease (LEAD) and 24 patients with CLTI (25 limbs) from March 2021 to December 2024; blood flow in the dorsal and plantar areas was measured using a portable LDF (Pocket LDF, JMS Co., Ltd., Tokyo, Japan). Blood flow and skin perfusion pressure (SPP) were compared before and after surgical bypass, and correlations between LDF and SPP were also determined for 17 limbs with CLTI.
Results:
The mean dorsal plantar blood flow was 12.0 ± 9.3 and 13.3 ± 6.6 mL/min for the non-LEAD and CLTI groups, respectively (p = .48), however, the mean plantar blood flow was statistically significant lower in the CLTI group (26.1 ± 11.7 mL/min) than in the non-LEAD group (52.2 ± 18.6 mL/min, p < .001). In the 17 limbs with CLTI that underwent surgical bypass, the mean blood flow in the dorsal area was 13.7 ± 5.5 and 15.7 ± 6.2 mL/min before and after surgery, respectively (p = .30). However, the post-operative mean plantar blood flow improved statistically significant (45.4 ± 18.6 mL/min) from its pre-operative status (25.0 ± 11.8 mL/min, p < .001). The mean SPP changes before and after surgical bypass were 27.3 ± 14.7 and 52.7 ± 18.3 mmHg, respectively (p < .001), in the dorsal area, showing improvement in correlation with the LDF measurements (p = .023).
Conclusion:
The portable LDF measurement in the plantar area may help in identifying CLTI and evaluating the effectiveness of revascularisation.
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