Feasibility of Portable Laser Doppler Flowmeter for Foot Blood Flow Assessment in Patients With Chronic Limb

Masahiro Tezuka1, Shotaro Hirota1, Masashi Kawamura1

  • 1Department of Cardiac and Vascular Surgery, Dokkyo Medical University, Mibu, Tochigi, Japan.

EJVES Vascular Forum
|October 29, 2025
PubMed

Insights

Portable laser Doppler flowmetry (LDF) effectively identifies chronic limb-threatening ischemia (CLTI) by measuring plantar blood flow. This non-invasive technique also accurately assesses the success of revascularization procedures in CLTI patients.

Area of Science:

  • Vascular Surgery
  • Medical Devices
  • Diagnostic Technologies

Background:

  • Chronic limb-threatening ischemia (CLTI) requires accurate assessment of lower extremity blood flow.
  • Non-invasive methods are crucial for bedside evaluation of peripheral arterial disease.
  • Laser Doppler flowmetry (LDF) offers a portable solution for blood flow measurement.

Purpose of the Study:

  • To evaluate the capability of portable laser Doppler flowmetry (LDF) in identifying CLTI.
  • To assess the utility of LDF in determining the efficacy of revascularization in CLTI patients.
  • To compare LDF measurements with skin perfusion pressure (SPP).

Main Methods:

  • A prospective study involving patients with and without CLTI.
  • Blood flow measurement in dorsal and plantar areas using a portable LDF device.
  • Comparison of LDF and SPP before and after surgical bypass in CLTI limbs.

Main Results:

  • Plantar blood flow was significantly lower in the CLTI group compared to the non-lower extremity arterial disease (LEAD) group (p < .001).
  • Post-operative plantar blood flow significantly improved after surgical bypass (p < .001).
  • LDF measurements showed significant correlation with SPP changes post-revascularization (p = .023).

Conclusions:

  • Portable LDF is a valuable tool for identifying CLTI.
  • Plantar LDF measurements can effectively evaluate the success of revascularization.
  • LDF provides a practical, non-invasive method for bedside assessment in CLTI management.
Abstract

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