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Postnatal Growth of Moroccan Preterm Infants: Determinants of Incomplete Catch-up Growth and Z-Score Trajectories in

Latifa Mochhoury1, Khaddouj Elgoundali1, Milouda Chebabe1

  • 1Higher Institute of Health Sciences, Hassan First University of Settat, Settat, Morocco.

Journal of Research in Health Sciences
|October 29, 2025
PubMed

Insights

Premature infants born at ≥32 weeks and those from multiparous mothers showed better growth outcomes. Longer hospital stays negatively impacted growth in preterm infants, highlighting the need for targeted nutritional support.

Area of Science:

  • Neonatology
  • Pediatric Growth and Development
  • Public Health Nutrition

Background:

  • Prematurity and neonatal hypotrophy are significant risk factors for adverse perinatal outcomes and long-term developmental issues.
  • Understanding growth trajectories in preterm infants is crucial for early intervention and improved health outcomes.
  • This study focuses on Moroccan preterm infants, addressing a specific regional health concern.

Purpose of the Study:

  • To examine the growth trajectories of preterm infants in Morocco up to six months of age.
  • To identify factors influencing the weight, length, and head circumference growth outcomes of these infants.
  • To provide data for developing targeted nutritional and clinical support strategies.

Main Methods:

  • A retrospective longitudinal cohort study involving 686 preterm newborns (24-36 weeks) with six-month follow-up.
  • Exclusion of infants with major malformations, chromosomal abnormalities, metabolic disorders, or incomplete data.
  • Statistical analysis using ANOVA and multivariate logistic regression to determine predictors of weight growth outcomes (WAZ≥-2).

Main Results:

  • Infants born at gestational age ≥32 weeks had significantly better growth outcomes (OR=6.66).
  • Multiparity was a strong predictor of positive growth outcomes (OR=12.09).
  • Hospital stays of ≥10 days were associated with reduced growth likelihood (OR=0.05).

Conclusions:

  • Gestational age and multiparity are key positive predictors for preterm infant growth.
  • Extended hospitalization poses a risk to postnatal growth, necessitating focused interventions.
  • Close monitoring and tailored nutritional strategies are vital for optimizing growth in preterm populations.
Abstract

Keywords:
BreastfeedingFetal growth retardationGrowth and developmentInfantNutritional statusPremature

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