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Can Artificial Intelligence Revolutionise Surgical Decision-Making for Appendectomy? A Narrative Review
Ali Murtada1, Marco David Bokobza De la Rosa2, Fatima Kayali3
1Department of General Surgery, Glan Clwyd Hospital, Rhyl, UK.
Surgical Innovation
|October 29, 2025
Summary
Artificial Intelligence (AI) significantly improves acute appendicitis diagnosis and prognosis, outperforming traditional methods. Further standardization is needed for clinical integration of these advanced machine learning models.
Area of Science:
- Medical Imaging
- Computational Biology
- Surgical Diagnostics
Background:
- Acute appendicitis is a frequent cause of acute abdomen, yet misdiagnosis and negative appendectomies persist.
- Advancements in Artificial Intelligence (AI), including machine learning (ML) and deep learning, offer potential solutions for diagnostic challenges.
Purpose of the Study:
- To review the literature on AI's application in diagnosing and prognosing acute appendicitis.
- To assess the efficacy of various AI models compared to traditional diagnostic scores.
Main Methods:
- Conducted a literature review of studies on AI for appendicitis diagnosis and prognosis.
- Included studies from PubMed and Cochrane databases, excluding those solely based on clinical or radiology reports.
Main Results:
- AI models, particularly random forest (RF), demonstrated high diagnostic accuracy, surpassing traditional scores like the Alvarado score.
- Machine learning methods (SVM, XGBoost) effectively predicted prognosis and identified complicated appendicitis cases.
- Neural networks (NN) and logistic regression (LR) also showed promising results in diagnosis.
Conclusions:
- AI holds significant potential to improve acute appendicitis diagnosis and prognosis.
- Addressing data requirements and standardization is crucial for widespread clinical adoption of AI in appendicitis management.
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