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Reducing Vaccination Pain in Infants: A Randomized Controlled Trial on the Effects of ShotBlocker and Manual Pressure

Şeyma Kışlalı Taş1, Dilek Sari2, Nihal Taşkıran3

  • 1Manisa Soma No. 5 Family Health Center, Manisa, Turkey.

Clinical Pediatrics
|October 29, 2025
PubMed

Insights

Neither ShotBlocker nor manual pressure reduced pain for infants during pneumococcal conjugate vaccine (PCV) shots. Further research is needed for effective infant pain management during vaccinations.

Area of Science:

  • Pediatrics
  • Immunology
  • Pain Management

Background:

  • Infant vaccinations can be a painful experience.
  • Effective nonpharmacological pain management strategies are crucial for infants during immunizations.

Purpose of the Study:

  • To evaluate the efficacy of ShotBlocker and manual pressure in reducing pain during pneumococcal conjugate vaccine (PCV) administration in 4-month-old infants.
  • To compare pain scores between infants receiving PCV with ShotBlocker, manual pressure, or no intervention.

Main Methods:

  • A randomized experimental study involving 102 4-month-old infants receiving PCV.
  • Participants were randomly assigned to ShotBlocker, manual pressure, or control groups (34 infants each).
  • Pain was assessed using the Neonatal Infant Pain Scale (NIPS) and video recordings.

Main Results:

  • No statistically significant difference in NIPS scores was observed among the ShotBlocker, manual pressure, and control groups (F = 0.789, P > .05).
  • Neither ShotBlocker nor manual pressure demonstrated effectiveness in reducing pain during PCV administration in this infant cohort.

Conclusions:

  • Current nonpharmacological methods like ShotBlocker and manual pressure are not effective for pain reduction in 4-month-old infants during PCV vaccination.
  • There is a need to explore and develop alternative, specific nonpharmacological pain management strategies for infant immunizations.

Keywords:
ShotBlockerinfantmanual pressurepainvaccine

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