Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Critical role of keratinocytes and protease-activated receptor 2 in secondary lymphedema development.

Clinical and translational medicine·2026
Same author

Longitudinal Trends in wRVU and Reimbursement for Free Flap and Implant-Based Breast Reconstruction: A 13-Year Valuation Analysis.

Plastic and reconstructive surgery·2026
Same author

Keratinocytes: A key player in skin immunity and their emerging roles in secondary lymphedema.

JID innovations : skin science from molecules to population health·2026
Same author

Breast Implant-Associated Malignancies: Current Recommendations for Workup and Management.

Plastic and reconstructive surgery·2026
Same author

Isolation and Culture of Primary Keratinocytes from Human Skin Grafts.

Methods in molecular biology (Clifton, N.J.)·2026
Same author

Racial Disparities in Oncoplastic Reduction Mammoplasty and Mastopexy Outcomes.

Plastic and reconstructive surgery·2026
Same journal

Building Practical Artificial Intelligence Tools For The Plastic Surgeon: A Step-By-Step Guide To Cowork.

Plastic and reconstructive surgery·2026
Same journal

Interpretation Matters: Common Statistical Pitfalls in Retrospective Surgical Research.

Plastic and reconstructive surgery·2026
Same journal

"Inferior Repositioning of the High-Riding Nipple Using a Parenchymal-Based Flap".

Plastic and reconstructive surgery·2026
Same journal

A Four-Step Strategy for the Treatment of Facial Rhytids: A Focus on Upper Facial Wrinkles.

Plastic and reconstructive surgery·2026
Same journal

Evaluating Long-Term Retention of Fresh-Frozen Costal Cartilage Allograft in An Animal Model.

Plastic and reconstructive surgery·2026
Same journal

Manual extrusion of fat granules for primary thinning of a bulky flap.

Plastic and reconstructive surgery·2026
See all related articles

Related Experiment Video

Updated: Jan 13, 2026

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

6.9K

Reconstructing Segmental Mandibular Defects: A Single-Center, 21-Year Experience with 413 Fibula Free Flaps.

Robert J Allen1, Kevin K Zhang1, Zack Cohen1

  • 1From the Plastic and Reconstructive Surgery Service.

Plastic and Reconstructive Surgery
|October 29, 2025
PubMed
Summary
This summary is machine-generated.

Fibula free flap (FFF) reconstruction for mandible defects has evolved with new technologies. While improving workflow and dental rehabilitation, FFF mandible reconstruction remains a high-risk procedure with significant morbidity.

More Related Videos

Coronoid-Temporalis Pedicled Flap for Orbital Floor Defect Reconstruction
06:32

Coronoid-Temporalis Pedicled Flap for Orbital Floor Defect Reconstruction

Published on: December 5, 2025

551
Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
08:01

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach

Published on: August 24, 2018

9.4K

Related Experiment Videos

Last Updated: Jan 13, 2026

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

6.9K
Coronoid-Temporalis Pedicled Flap for Orbital Floor Defect Reconstruction
06:32

Coronoid-Temporalis Pedicled Flap for Orbital Floor Defect Reconstruction

Published on: December 5, 2025

551
Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
08:01

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach

Published on: August 24, 2018

9.4K

Area of Science:

  • Oral and Maxillofacial Surgery
  • Reconstructive Surgery
  • Oncology

Background:

  • The fibula free flap (FFF) is a standard for mandibular reconstruction post-oncologic resection.
  • Technological and surgical advancements have altered FFF workflow and outcomes.

Purpose of the Study:

  • To analyze institutional experience with evolving FFF techniques for mandible reconstruction.
  • To assess the impact of these changes on patient outcomes and procedural efficiency.

Main Methods:

  • A 21-year retrospective review of patients undergoing segmental mandibulectomy with FFF reconstruction.
  • Analysis of surgical planning, fixation methods, complication rates, and rehabilitation outcomes.

Main Results:

  • 413 FFFs in 401 patients over 21 years; average procedure length 675.6 minutes.
  • Increased use of computer-aided design and manufacturing (CAD/CAM) and immediate dental implant placement (IDIP) correlated with higher dental rehabilitation rates.
  • Flap success rate was 97.8%, but 54.7% experienced complications, and all-cause mortality was 43.6%.

Conclusions:

  • Modern FFF techniques and technology have enhanced operative workflow and patient outcomes in mandible reconstruction.
  • Despite advancements, FFF-based mandible reconstruction continues to be a procedure associated with significant morbidity.