Related Experiment Video
Updated: Jan 6, 2026

Synchronization of Caulobacter Crescentus for Investigation of the Bacterial Cell Cycle
Published on: April 8, 2015
Influence of bacterial proteins on the host's cell cycle
Francesca Benedetti1, Camila Summers1, Robert C Gallo1,2
1Institute for Translational Virology and Innovation, Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
None:
Bacterial proteins released into the cellular microenvironment are increasingly recognized as pivotal modulators of host key signaling pathways, with significant implications for cellular functions. This review explores the multifaceted roles of such bacterial proteins, often functioning as virulence factors, in modulating the host cell cycle. By focusing on the interactions between selected bacterial proteins and essential components of the cell cycle machinery, we describe the mechanisms through which these interactions disrupt relevant cellular functions and contribute to disease development, with a particular focus on cancer.
Related Concept Videos
Cytoskeletal Proteins in Bacteria
Negative Regulator Molecules
Intracellular Movement of Viruses and Bacteria
Molecular Factors Affecting Cell Division
Several proteins function as internal regulators to ensure each cell cycle stage is completed faithfully before proceeding to the next. Regulator molecules may act directly or influence the activity or production of other...
Coordination of Gene Expression Processes in Bacteria
Lysogenic Cycle of Bacteriophages

