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Research on childhood asthma and vitamin D (2003-2023): a bibliometric analysis
NaiXu Liu1,2, Fei Luo1,2, XiaoRui Chen1,2
1Department of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Insights
Research on Vitamin D (Vit D) and childhood asthma is developing, with limited consensus on mechanisms. More international collaboration and high-quality studies are needed to improve prevention and treatment strategies for this common childhood condition.
Area of Science:
- Pediatric Allergy and Immunology
- Nutritional Science
- Public Health
Background:
- Childhood asthma is a significant health concern, characterized by chronic airway inflammation.
- Vitamin D (Vit D) is increasingly recognized for its role in asthma development and progression.
- Bibliometric analyses specifically on the Vit D-childhood asthma nexus are lacking.
Purpose of the Study:
- To systematically review research status, hotspots, and trends in Vit D and childhood asthma.
- To establish a comprehensive knowledge network for future research.
- To provide a reference for researchers in the field.
Main Methods:
- Bibliometric analysis of 656 articles from Web of Science Core Collection (2003-2023).
- Data extraction and visualization using CiteSpace and VOSviewer.
- Retrospective search focusing on Vitamin D and childhood asthma.
Main Results:
- The United States leads in publications, followed by China and the UK.
- Key research themes include T cells, inflammation, prenatal factors, and comorbidities.
- The Journal of Allergy and Clinical Immunology is a primary publication venue.
Conclusions:
- Research on Vit D and childhood asthma is nascent, lacking consensus on mechanisms and comorbidities.
- Significant regional disparities in research output exist.
- Enhanced international collaboration and rigorous research are crucial for advancing understanding and clinical practice.
Background:
Asthma is a complex chronic inflammatory airway disease and one of the major health threats to children. Vitamin D (Vit D), an essential micronutrient, has been closely linked to the development and progression of asthma. However, there is still a lack of bibliometric analyses focusing on the relationship between Vit D and childhood asthma.
Objective:
This study aims to systematically review the current research status, hotspots, and future trends in this field using bibliometric methods, providing a more comprehensive knowledge network and reference for related research.
Methods:
A retrospective search was conducted in the Web of Science Core Collection (WoSCC) database for studies related to Vit D and childhood asthma published from January 2003 to December 2023. CiteSpace and VOSviewer were used to extract and analyze the data and to generate visual knowledge maps.
Results:
A total of 656 articles were included. The United States ranked first in publication volume, followed by China and the United Kingdom. The Journal of Allergy and Clinical Immunology had the highest number of publications. Core research keywords included T cells, inflammation, in utero exposure and prenatal factors, as well as asthma-related comorbidities.
Conclusions:
Research on the relationship between Vit D and childhood asthma remains in a developmental stage, with no established consensus regarding its underlying mechanisms, contributing factors, or associated comorbidities. Regional disparities remain significant. Strengthening cross-regional collaboration and conducting high-quality clinical and basic research is essential to advance understanding and improve prevention and treatment strategies.
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