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Updated: Jan 13, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Poststreptococcal Glomerulonephritis Secondary to Bacterial Vaginosis, Complicated by Hemolytic Anemia and
Takafumi Shiga1, Keisuke Onishi1, Hirona Nagano1
1Department of CardioRenal and CerebroVascular Medicine, Faculty of Medicine, Kagawa University, Japan.
Abstract:
A 65-year-old woman diagnosed with group A streptococcal vaginosis was admitted to our hospital with pyothorax. Abscess drainage was performed, and antimicrobial agents were administered; however, hematuria, proteinuria, hemolytic anemia, thrombocytopenia, and renal dysfunction developed. Conservative management did not improve kidney or systemic conditions. A renal biopsy confirmed post-infectious glomerulonephritis (PIGN). Glucocorticoid treatment improved the kidney and systemic findings. Bacterial vaginosis rarely causes PIGN. Hemolytic anemia and thrombocytopenia are infrequent complications of PIGN, and glucocorticoids may be effective for their treatment.
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