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Genome Skimming Reveals Genetic Diversity in 220 Papaver Individuals from China

  • 0China Agriculture Research System (CARS-21) and Gansu Provincial Key Laboratory of The Special Medine Source Plant for Germplasm Innovation and Safety Utilization, Gansu Academy of Agri-Engineering Technology, Room 1401-1411, Floor 14, No.18, Gaoxin Yan South Road, Chengguan District, Lanzhou, 730030, Gansu, China.
Scientific Data +

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October 30, 2025

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October 30, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

This study presents the largest poppy genetic dataset, offering valuable insights into medicinal Papaver traits and aiding in anti-drug forensic tracing. These findings support pharmacological research and molecular breeding of Papaver varieties.

Area Of Science

  • Genomics
  • Pharmacology
  • Medicinal Botany

Background

  • Papaver species are crucial medicinal plants, serving as the primary source for morphine and codeine in China.
  • Understanding Papaver genetics is vital for identifying key traits, medicinal properties, and for forensic applications.
  • Limited genetic data has hindered comprehensive research on diverse Papaver varieties.

Purpose Of The Study

  • To conduct whole-genome sequencing of a large number of Papaver samples.
  • To identify valuable genetic markers for understanding Papaver traits and properties.
  • To establish a comprehensive genetic resource for future research and applications.

Main Methods

  • Whole-genome sequencing of 220 samples across 22 Papaver species.
  • Processing of approximately 5.12 TB of paired-end reads with 10.2X average coverage depth.
  • Identification of 2,790,225 single nucleotide polymorphisms (SNPs) after alignment to a reference genome.

Main Results

  • Generated the largest publicly available poppy genetic dataset to date.
  • Achieved a high alignment rate of 98.02% to the reference genome.
  • Identified a substantial number of single nucleotide polymorphisms (SNPs) for genetic analysis.

Conclusions

  • The generated dataset provides critical genetic information for Papaver research in China.
  • This resource will facilitate future studies on pharmacological properties, molecular breeding, and genomic tracing of Papaver.
  • The findings support the development of Papaver-based medicinal applications and forensic tools.