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Associations Between Neighborhood Environment, Childhood Adversity, and Cancer Risk: A Geospatial Analysis.

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Neighborhoods with high childhood trauma and low cancer prevention behaviors face higher cancer mortality. Trauma-informed interventions can help tailor cancer prevention efforts at the neighborhood level.

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Area of Science:

  • Public Health
  • Environmental Health
  • Socio-ecological Models

Background:

  • Childhood trauma is a significant public health concern.
  • Cancer prevention behaviors are crucial for reducing cancer mortality.
  • The built environment can influence health outcomes.

Purpose of the Study:

  • To investigate the association between neighborhood-level childhood trauma, cancer prevention behaviors, and cancer mortality in Philadelphia.
  • To explore the socio-ecological factors influencing cancer outcomes.

Main Methods:

  • Utilized cancer registry data and neighborhood-level risk factors (trauma and cancer prevention adherence).
  • Performed multivariate linear regression analyses to assess relationships.
  • Geospatially visualized associations between risk factors and cancer mortality.

Main Results:

  • Childhood trauma and cancer prevention adherence explained 50% of the variation in neighborhood cancer mortality.
  • High cancer mortality neighborhoods often exhibited high trauma measures.
  • Geographic proximity correlated with shared risk factors.

Conclusions:

  • Neighborhoods with high cancer mortality are linked to high trauma and low cancer prevention behaviors.
  • Neighborhood-level trauma data can inform targeted, trauma-informed cancer prevention strategies.
  • Findings emphasize the importance of socio-ecological approaches in cancer control.