Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

465
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
465
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

15.3K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
15.3K
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

1.5K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
1.5K
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

3.9K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
3.9K
Odds Ratio01:09

Odds Ratio

1.6K
The odds ratio (OR) is a statistical measure used extensively in epidemiology and research to quantify the strength of association between exposure and outcome across different groups. Unlike relative risk, which compares the probabilities of an event occurring, the odds ratio compares the odds of an event occurring in the exposed group to the odds of it occurring in the unexposed group. The odds, in this context, are calculated as the probability of the event happening divided by the...
1.6K
Correlations02:20

Correlations

35.7K
Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...
35.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Case Report: pharmaceutical care in a case of complicated urinary tract infection combined with disseminated <i>Nocardia brasiliensis</i> infection.

Frontiers in medicine·2026
Same author

Sex-Specific Adverse Events and Cardiovascular Toxicity of Cabozantinib in Renal Cell Carcinoma: A Nine-Year Pharmacovigilance Study.

Cancer investigation·2026
Same author

Visceral adipose tissue and risk of kidney stones: Evidence from NHANES 2011-2018 and Mendelian randomization analysis.

Medicine·2026
Same author

Development and validation of machine learning prognostic models for overall survival in non-surgical prostate cancer patients with bone metastases.

The aging male : the official journal of the International Society for the Study of the Aging Male·2026
Same author

Correction: Post-marketing safety of pentosan polysulfate sodium: a 21-year pharmacovigilance analysis of the FAERS database.

Frontiers in medicine·2026
Same author

Post-marketing safety of pentosan polysulfate sodium: a 21-year pharmacovigilance analysis of the FAERS database.

Frontiers in medicine·2026
Same journal

The Clinical, Humanistic, and Economic Burden of Idiopathic Hypersomnia in the United States: Analysis of the National Health and Wellness Survey.

Nature and science of sleep·2026
Same journal

A Nomogram Model for Predicting Moderate to Severe OSA in Western China: A Retrospective Analysis.

Nature and science of sleep·2026
Same journal

Content Validity and Psychometric Evaluation of the Idiopathic Hypersomnia Severity Scale (IHSS) in Adults with Idiopathic Hypersomnia.

Nature and science of sleep·2026
Same journal

The Prognostic Value of Early Treatment Factors for Cognitive Behavioral Therapy for Insomnia (CBT-I) Outcomes.

Nature and science of sleep·2026
Same journal

Follow-up Study on the Sleep Status of Anti-Epidemic Staff: A Study Based on Wearable Sleep Trackers.

Nature and science of sleep·2026
Same journal

Prevalence of Insomnia in Healthcare Profession - PIHEP Study: A Large-Scale National Study in Vietnam.

Nature and science of sleep·2026
See all related articles

Related Experiment Video

Updated: Jan 12, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.5K

Association Between Obstructive Sleep Apnea and Prostate Cancer: NHANES and the Mendelian Randomization Study.

Ying Liu1,2, Binglei Jiang3, Long Xia2

  • 1Department of Transfusion, Zigong First People's Hospital, Zigong, Sichuan, People's Republic of China.

Nature and Science of Sleep
|October 30, 2025
PubMed
Summary
This summary is machine-generated.

Obstructive sleep apnea (OSA) shows no overall link to prostate cancer. However, a negative association was found in younger men, suggesting age-specific effects warranting further study.

Keywords:
mendelian randomizationnational health and nutrition examination surveyobstructive sleep apneaprostate cancer

More Related Videos

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD &#8212; A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

1.3K
Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
05:34

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

3.3K

Related Experiment Videos

Last Updated: Jan 12, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.5K
Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD &#8212; A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

1.3K
Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
05:34

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

3.3K

Area of Science:

  • Urology
  • Sleep Medicine
  • Oncology

Background:

  • Obstructive sleep apnea (OSA) is a prevalent global condition.
  • Prostate cancer is the most common cancer in men.
  • The relationship between OSA and prostate cancer risk is not well-established.

Purpose of the Study:

  • To investigate the association between obstructive sleep apnea and prostate cancer.
  • To explore potential age-specific relationships between OSA and prostate cancer.
  • To determine if OSA causally influences prostate cancer risk.

Main Methods:

  • Multivariable regression analysis was performed on NHANES data.
  • Age-stratified analyses were conducted to examine different age groups.
  • Mendelian randomization was utilized to assess causality.

Main Results:

  • Overall multivariable regression showed no significant association between OSA and prostate cancer (OR = 0.83; 95% CI: 0.46-1.48).
  • Age-stratified analysis revealed a significant negative correlation in men younger than 60 (OR = 0.07; 95% CI: 0.01-0.74).
  • No significant association was observed in men aged 60 and older (OR = 1.01; 95% CI: 0.69-1.49).
  • Mendelian randomization did not support a causal link between OSA and prostate cancer (OR = 0.992; 95% CI: 0.876-1.124).

Conclusions:

  • No overall association between OSA and prostate cancer was found.
  • A significant negative correlation between OSA and prostate cancer was observed in younger men (<60 years).
  • Further research is needed to elucidate potential biological mechanisms and confirm findings.