Unveiling the Mysteries of Ameloblastoma: A Comprehensive Case Series on Odontogenic Lesions

Ameloblastoma is a benign yet locally invasive odontogenic tumor arising from remnants of the enamel organ or dental lamina, typically manifesting as painless jaw swelling associated with impacted teeth. Its marked histopathological heterogeneity necessitates precise diagnosis to avert recurrence. This case series presents four diverse ameloblastoma variants, including conventional, unicystic (luminal and mural), and a rare mimic of a lateral periodontal cyst. Clinical, radiographic, and histological evaluations were conducted, revealing hallmark features such as peripheral palisading, stellate reticulum-like zones, and cystic degeneration. The findings highlight the indispensability of integrated diagnostic protocols and timely surgical intervention for effective management.