An In-vitro Assessment of Potassium Iodide and Glutathione on Color Change Caused by Silver Diamine Fluoride...

To assess and contrast the impact of glutathione (GSH) and potassium iodide (KI) on tooth discoloration brought on by silver diamine fluoride (SDF) treatment on primary incisors.

Standardized 2 mm × 2 mm (depth × width) of cavities were made on labial surface of each specimen, and artificial caries was created on 40 extracted primary incisors and divided into four groups based on the solution used as follows: group 1 - SDF, group 2 - SDF + saturated KI, group 3 - SDF + GSH, and group 4 - distilled water. The color assessment was recorded on days 1, 7, and 14 by using a spectrophotometer.

SDF caused maximum staining. Staining in groups 2 and 3 was significantly less (P < 0.05) compared to SDF, while group 3 showed the least staining at days 1 and 7, but the staining increased gradually and had no statistical difference at 14 days when compared to group 2.

The use of GSH along with SDF helps in reducing the discoloration.