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Updated: Jan 12, 2026
Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
Published on: March 13, 2018
Enhancing Dengue Surveillance in Remote Tribal Communities of Chhattisgarh through Integrated Serological
Rani Soni1,2, Dhananjay Tandon1, Debashish Samal2
1Department of Applied Science, Shri Rawatpura Sarkar University, Raipur, Chhattisgarh, India.
Introduction:
Dengue fever is a significant public health issue, affecting nearly 100 million people globally each year.
Aim:
This study investigates dengue infection trends, particularly focusing on thrombocytopenia and neurological symptoms in confirmed cases.
Materials And Methods:
A total of 1,558 blood samples were collected from probable dengue patients. Serological tests for NS1 antigen detection and IgM/IgG antibody titers were performed using enzyme-linked immunosorbent assay (ELISA).
Results:
In total, 166 samples (10.65%) out of 1,558 tested positive for dengue. IgM showed the highest positivity (40.47%), followed by NS1 antigen (37.5%). Males were more frequently affected than females, with a male-to-female ratio of 1.8:1. The age group of 21-30 years accounted for the largest number of cases (32.14%). Thrombocytopenia was observed in 88.09% of dengue-positive cases, with 26.19% having platelet counts below 50,000 cells/cumm. A few pediatric patients displayed severe neurological complications, including encephalitis, meningitis, and encephalopathy.
Conclusion:
This study highlights the importance of using IgG/IgM ratios to differentiate primary from secondary dengue infections; in addition, to control the severity of the disease, regular thrombocyte measurement is required and is highly recommended.
