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Enhancing Clear Aligners Therapy with Artificial Intelligence and Technology.

¹Clinical Project Manager, InBrace, Irvine, CA, USA.

Journal of Pharmacy & Bioallied Sciences

|October 30, 2025

Summary

An AI mobile app significantly improved patient engagement and adherence in clear aligner therapy (CAT). The StrojCHECK app enhanced treatment outcomes, particularly for women, by providing individualized feedback and real-time alerts.

Keywords:

Artificial intelligence clear aligner therapy orthodontic treatment smart application

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Area of Science:

Orthodontics
Digital Health
Artificial Intelligence

Background:

Clear aligner therapy (CAT) efficacy relies heavily on patient compliance.
Proper aligner use is critical for successful malocclusion management.

Purpose of the Study:

To investigate the impact of an AI mobile application (StrojCHECK®) on patient participation in CAT.
To assess the influence of AI-driven features on treatment adherence.

Main Methods:

A cohort of 55 patients (aged 12-68) was monitored before and after an AI system update.
The updated AI system included decision trees, personalized feedback, and real-time alerts.

Main Results:

Patient app engagement scores increased from 4.2 to 7.3.
Clinical aligner tracking adherence improved from 85% to 92%.
Non-compliance significantly decreased in women (10% to 5%, P < 0.05), while male compliance remained unchanged.

Conclusions:

Behavioral data collection and individualized feedback are vital for treatment success.
AI in digital healthcare can substantially boost patient compliance in orthodontics.