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Anticoagulation Therapy May Reduce Subsegmental Nonocclusive Inferior Vena Cava Filter-Related Thrombus Burden: A

Pengkai Cao1, Xintong Luo2, Yunsong Li1

  • 1Vascular Surgery Department of Third Hospital of Hebei Medical University, Shijiazhuang, China.

Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists
|October 30, 2025
PubMed

Insights

Anticoagulation therapy effectively reduces filter-related thrombus burden. Longer anticoagulation periods and suprarenal inferior vena cava filter placement improve thrombus resolution, potentially enhancing filter retrieval rates.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Cardiovascular Medicine

Background:

  • Inferior vena cava filters (IVCFs) are used to prevent pulmonary embolism.
  • Filter-related thrombus can complicate IVCF management and retrieval.
  • Subsegmental nonocclusive thrombus is a specific type of IVCF-related complication.

Purpose of the Study:

  • To assess the efficacy of anticoagulation therapy for subsegmental nonocclusive filter-related thrombus.
  • To identify risk factors influencing thrombus volume changes.
  • To evaluate outcomes based on IVCF location (infrarenal vs. suprarenal).

Main Methods:

  • Retrospective single-center study of patients with IVCF placement and retrieval (July 2018 - December 2023).
  • Inclusion criteria: subsegmental nonocclusive filter-related thrombus.
  • Data collected: demographics, medical history, IVCF details, anticoagulation duration, and outcomes.

Main Results:

  • Two groups studied: infrarenal IVCF (n=32) and suprarenal IVCF (n=38).
  • Suprarenal group had significantly longer anticoagulation time before IVCF removal (74.47 vs. 51.25 days).
  • Higher thrombus resolution rates in the suprarenal group (38/38 complete/partial vs. 29/32 in infrarenal group); infrarenal group had 3 cases of progressed thrombus.

Conclusions:

  • Anticoagulation therapy is effective in reducing filter-related thrombus burden.
  • Longer anticoagulation duration and suprarenal IVCF placement are associated with better thrombus resolution.
  • Findings suggest improved options for managing filter-related thrombus and potentially higher IVCF retrieval rates.
Abstract

Keywords:
anticoagulationfilterinferior vena cavaretrievalthrombus

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