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Pertussis: Modern Approaches to an Ancient Adversary
C Buddy Creech1, Dakota Musgrave1
1Vanderbilt Vaccine Research Program, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, United States.
None:
Despite widespread vaccination, the United States has seen a stark increase in pertussis cases over the past year. Disease profiles vary across age groups, with infants at the greatest risk. The development of next generation pertussis vaccines will involve updated antigenic content, novel adjuvants, and live-attenuated constructs, potentially leveraging controlled human infection models of pertussis.
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