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Strategies to predict and decrease flow rate pulsation in a rotary peristaltic pump with novel tube design.

Alexandros Anastasiadis1,2, Nikolaos Rogkas3, Achileas Tsoukalis4

  • 1Laboratory of Machine Design and Dynamics, National Technical University of Athens, Athens, Greece.

Medical & Biological Engineering & Computing
|October 30, 2025
PubMed
Summary

This study reduced peristaltic pump flow pulsations by 23% using optimized geometry and housing modifications. These improvements are crucial for medical applications like drug infusion and cardiopulmonary bypass, minimizing fluid strain and potential hemolysis.

Keywords:
Elastic tubeFlow ratePeristaltic pumpPulsating flowSimulation

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Area of Science:

  • Biomedical Engineering
  • Fluid Dynamics
  • Medical Device Design

Background:

  • Peristaltic pumps are vital in medical applications (e.g., cardiopulmonary bypass, drug infusion) due to non-contact fluid handling and precise flow control.
  • Inherent flow pulsations in peristaltic pumps can cause adverse effects like hemolysis in blood.
  • Understanding and mitigating these pulsations is critical for enhancing the safety and efficacy of medical fluid delivery systems.

Purpose of the Study:

  • To investigate the underlying mechanics of output mass flow rate pulsations in peristaltic pumps.
  • To explore and quantify strategies for reducing these flow pulsations.
  • To introduce a cost-effective method for estimating mass flow rate trends.

Main Methods:

  • Conducted 3D fluid-structure interaction (FSI) simulations using optimized tube geometry under realistic operating conditions.
  • Monitored pressure variations before and after pump rollers to correlate with flow rate fluctuations.
  • Analyzed the impact of geometric parameters (roller diameter, tube stiffness, curvature) and housing support on flow pulsation.

Main Results:

  • Identified a direct correlation between pressure variations during roller disengagement and transient drops in mass flow rate.
  • Optimizing roller diameter reduced flow pulsation by 20%; tube wall stiffness and curvature radius showed minimal impact.
  • Removing external pump housing support near the outlet decreased flow pulsation by up to 23% through smoother roller disengagement.

Conclusions:

  • Optimized geometric design and strategic housing modification are effective in significantly reducing peristaltic pump flow pulsations.
  • These findings offer practical strategies for improving the performance and reliability of peristaltic pumps in critical medical applications.
  • A validated volumetric approach provides a viable alternative for estimating mass flow rate, complementing CFD analysis.