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Updated: Jan 12, 2026

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats
Published on: March 8, 2019
[Pulmonary artery surgery in thoracic oncology]
V D Parshin1,2,3, Yu V Belov4, R N Komarov4
1National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Moscow, Russia.
Objective:
To improve the results of surgical treatment of locally advanced tumors invading pulmonary artery.
Material And Methods:
There were 51 patients with various tumors invading large intrathoracic vessels between 2005 and 2021. Cardiac surgical technologies and CPB were used in 32 (62.4%) patients. Mediastinal and lung tumors were observed in 38 (74.5%) and 13 (25.4%) patients, respectively.
Results:
The incidence of postoperative complications in combined surgeries associated with resection of large intrathoracic vessels was 53.3%, mortality rate - 8.2%.
Conclusion:
In thoracic oncology, resection and reconstruction of pulmonary arteries are possible in primary sarcoma and malignant tumors arising from the outside. These operations should be performed under CPB to achieving R0 resection.
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