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Updated: Jan 12, 2026

Models of Bone Metastasis
Published on: September 4, 2012
Trends in Palliative Care Utilization in Patients with Bone Metastases
Dana G Rowe1, Joshua Woo1, Seeley Yoo1
1Duke School of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Background:
Bone metastases cause significant symptom burden, yet patterns of palliative care (PC) utilization in this population remain poorly characterized.
Objectives:
To evaluate trends in PC use, compare inpatient palliative care (IPPC) and outpatient palliative care (OPPC) utilization, identify predictors of PC engagement, and assess the impact on readmissions.
Methods:
Using the PearlDiver database (2011-2021), patients with bone metastases were identified. PC encounters were classified as IPPC or OPPC. Trends were assessed with linear regression; predictors and outcomes were evaluated using multivariate logistic regression.
Results:
Of 471,713 patients, 17.2% received PC. Overall PC use did not increase significantly from 2011 to 2021 (p = 0.14), though OPPC rose from 0.7% to 2.6% (R2 = 0.87). Predictors of PC use included younger age (mean age 64 vs. 66 years, p < 0.001), female gender, higher comorbidity burden, Medicaid insurance, and region (p < 0.01 for all). Receipt of OPPC within six months of hospice was associated with 77% lower odds of readmission (Odds Ratio (OR): 0.23, 95% Confidence Interval (CI): 0.17-0.30, p < 0.001).
Conclusion:
PC utilization remains low in this population. OPPC use has modestly increased and is associated with reduced readmissions prior to hospice referral. Expanding OPPC may reduce hospitalizations and improve care quality.
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