Integrated Multimodal Approaches in Pediatric Palliative Oncology: A Systematic Review Focused on Infants and Toddlers
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Multidisciplinary pediatric palliative care improves quality of life for children with serious illnesses. Home care and symptom management, including pain therapy, are key interventions, though more research is needed for infants.
Area Of Science
- Palliative Care
- Pediatric Oncology
- Child Health
Background
- Pediatric palliative care enhances quality of life for children with cancer and life-limiting conditions.
- Increasing eligibility necessitates multidisciplinary and personalized care strategies.
Purpose Of The Study
- To systematically review effective interventions in pediatric palliative care.
- Focus on pharmacological assistance, home management, and nursing roles for children aged 0-2 years.
Main Methods
- Systematic review of literature from PubMed, CINAHL, Google Scholar, and Scopus (2000-2024).
- Analysis focused on interventions for infants and toddlers (0-2 years).
Main Results
- Multimodal approaches are crucial in pediatric palliative care.
- Key interventions include sedative drugs for symptom control, electronic monitoring, pain therapy, and home care.
- Families strongly prefer home-based care.
Conclusions
- Integrated, multidisciplinary care models are essential for critically ill children's well-being.
- Limited studies on the 0-2 age group and lack of standardized protocols are significant clinical practice limitations.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Continuing care describes the variety of health, personal, and social services provided over a prolonged period. The need for continuing care is increasing because people are living longer. Many people do not have families or others to care for them. Continuing care is mainly for patients who are disabled, functionally dependent, or suffering from a terminal disease. It is available within institutional settings or in homes. Examples include nursing centers or facilities, assisted living,...
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...