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Integrated Multimodal Approaches in Pediatric Palliative Oncology: A Systematic Review Focused on Infants and

Angela Prendin1, Martina Costa2, Gloria Angela Baracco3

  • 1Research grant, University Hospital of Padua, Padua, Italy.

In Vivo (Athens, Greece)
|October 30, 2025
PubMed

Insights

Multidisciplinary pediatric palliative care improves quality of life for children with serious illnesses. Home care and symptom management, including pain therapy, are key interventions, though more research is needed for infants.

Area of Science:

  • Palliative Care
  • Pediatric Oncology
  • Child Health

Background:

  • Pediatric palliative care enhances quality of life for children with cancer and life-limiting conditions.
  • Increasing eligibility necessitates multidisciplinary and personalized care strategies.

Purpose of the Study:

  • To systematically review effective interventions in pediatric palliative care.
  • Focus on pharmacological assistance, home management, and nursing roles for children aged 0-2 years.

Main Methods:

  • Systematic review of literature from PubMed, CINAHL, Google Scholar, and Scopus (2000-2024).
  • Analysis focused on interventions for infants and toddlers (0-2 years).

Main Results:

  • Multimodal approaches are crucial in pediatric palliative care.
  • Key interventions include sedative drugs for symptom control, electronic monitoring, pain therapy, and home care.
  • Families strongly prefer home-based care.

Conclusions:

  • Integrated, multidisciplinary care models are essential for critically ill children's well-being.
  • Limited studies on the 0-2 age group and lack of standardized protocols are significant clinical practice limitations.
Abstract

Keywords:
Oncologypainpalliative carepediatricsreview

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