Lung Malignancies

Andrea Liebowitz1, David Posawatz2, Daniel Wiener3

  • 1Department of Surgery, Division of Thoracic Surgery, 75 Francis Street, Boston MA 02115, USA.

Thoracic Surgery Clinics
|October 30, 2025
PubMed

Insights

Precision medicine revolutionizes lung cancer care with advanced screening, diagnostics, and personalized therapies. Multidisciplinary, individualized approaches are key to improving outcomes and reducing disparities.

Area of Science:

  • Oncology
  • Precision Medicine
  • Medical Technology

Background:

  • Lung cancer remains a leading cause of cancer-related mortality worldwide.
  • Traditional treatment approaches often lack personalization, leading to suboptimal outcomes.
  • There is a growing need for innovative strategies to improve lung cancer management.

Purpose of the Study:

  • To review the transformative impact of precision medicine on lung cancer care.
  • To highlight advancements in screening, diagnostics, and therapeutic interventions.
  • To emphasize the integration of novel technologies and personalized strategies.

Main Methods:

  • Comprehensive literature review of recent advancements in lung cancer research.
  • Analysis of innovations in imaging, biopsy, and surgical techniques.
  • Evaluation of the role of immunotherapy, targeted therapies, and artificial intelligence.

Main Results:

  • Precision medicine offers enhanced screening and diagnostic capabilities.
  • Personalized therapies, including immunotherapy and targeted treatments, show significant promise.
  • Minimally invasive surgery and tailored resection strategies improve patient outcomes.
  • Artificial intelligence integration aids in optimizing treatment decisions and predicting responses.

Conclusions:

  • Precision medicine, through multidisciplinary and individualized approaches, is transforming lung cancer management.
  • Technological innovations and personalized therapies are crucial for improving patient survival and quality of life.
  • Addressing health disparities is an integral component of advancing precision oncology for lung cancer.

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