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Analysis of Risk Factors and Circumferential Distribution of Exposed Cardiac Glands
Mingyang Fan1, Haiyang Hua2, Jingyi Yin1
1Chengde Medical College Chengde China.
JGH Open : an Open Access Journal of Gastroenterology and Hepatology
|October 31, 2025
Summary
Exposed cardiac glands are linked to lifestyle factors like drinking and diet, and conditions such as gastroesophageal reflux disease. These findings help understand the development and progression of these esophageal glands.
Area of Science:
- Gastroenterology
- Esophageal pathology
Background:
- Exposed cardiac glands in the esophagus are a condition requiring investigation into associated risk factors.
- Understanding their distribution is crucial for establishing a theoretical basis for their development.
Purpose of the Study:
- To identify risk factors for exposed cardiac glands.
- To analyze the circumferential distribution of these glands in the esophagus.
- To provide a theoretical foundation for their occurrence and progression.
Main Methods:
- Prospective enrollment of patients undergoing gastroscopy.
- Comparison of risk factors between patients with and without exposed cardiac glands.
- Utilizing radar mapping to study gland distribution.
Main Results:
- Identified waist circumference, drinking, irritating food, right-side sleeping, calcium antagonists, Helicobacter pylori infection, and GERD as risk factors.
- Observed that exposed cardiac glands typically appear on the lesser curvature and posterior wall of the distal esophagus.
Conclusions:
- Exposed cardiac glands correlate with gastroesophageal reflux disease (GERD), with similar prone sites.
- Reflux may cause exposed cardiac glands to coalesce and progress.
- Independent risk factors include waist circumference, drinking, irritating food, right-side sleeping, calcium antagonists, and H. pylori infection.
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