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Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
Published on: January 12, 2017
Comparative evaluation of four different calcium-based medicaments as an indirect pulp capping agent: An in vivo
Ray Anuja Awadhesh1, Nitin Kararia1, Deepak Kumar Sharma1
1Department of Conservative Dentistry and Endodontics, NIMS Dental College and Hospital, Jaipur, Rajasthan, India.
Context:
The choice of material for indirect pulp capping (IPC) may affect long-term pulp vitality, particularly with newer bioactive cements.
Aims:
The aim of this study was to compare the clinical and radiographic efficacy of TheraCal LC, Binar LC, calcium-enriched mixture (CEM) cement, and calcium hydroxide as IPC agents in mature permanent teeth with deep carious lesions.
Methods:
In this prospective randomized trial, 52 patients with deep caries and reversible pulpitis were divided into four groups (n = 13). Standardized IPC procedures and follow-ups at 21 days, 3 months, and 6 months included clinical and radiographic evaluations.
Statistical Analysis Used:
ANOVA and Tukey's post hoc tests analyzed pain (Visual Analog Scale scores); Chi-square tests compared categorical variables.
Results:
All materials maintained pulp vitality without significant differences (P > 0.05). CEM cement achieved 100% success with no radiographic abnormalities. TheraCal LC and Binar LC performed well, while calcium hydroxide showed slightly more failures and a higher incidence of PDL widening.
Conclusions:
All tested materials were effective IPC agents; however, bioactive materials (CEM cement and TheraCal LC) demonstrated superior clinical outcomes and sealing ability versus traditional calcium hydroxide.
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