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Updated: Jan 12, 2026
A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
Evaluation of ozonoid olive oil as an indirect pulp capping agent in permanent molars: A randomized clinical trial
Hemal Bajaj1, Rashmi Nair2, Labdhi Maloo2
1Department of Conservative Dentistry and Endodontics, Dr. Chakinala Dental Hospital, Hyderabad, Telangana, India.
Context:
Preserving pulp vitality is essential for maintaining tooth integrity, making indirect pulp capping (IPC) a preferred treatment for deep carious lesions. Traditional materials such as calcium hydroxide and mineral trioxide aggregate (MTA) promote dentin repair but have limitations.
Aims:
To evaluate the clinical success of ozonated olive oil as an IPC agent compared to MTA and Dycal in the treatment of deep carious lesions in permanent molars.
Subjects And Methods:
A randomized clinical trial was conducted on 60 patients aged 19-40 years, divided into three groups receiving IPC with ozonated olive oil, MTA, or Dycal. Clinical and radiographic evaluations were performed at 3 and 6 months to assess treatment success.
Results:
After 6 months, MTA had the best effectiveness rate (94%), followed by ozonated olive oil (89%) and Dycal (75%). Ozonated olive oil has shown considerable microbial reduction and dentin remineralization.
Conclusions:
Ozonated olive oil proved to be an effective IPC agent, exhibiting strong antimicrobial properties and promoting dentin remineralization.
Clinical Significance:
Ozonoid olive oil can be considered a potential indirect pulp capping agent in permanent teeth due to its antimicrobial properties and ability to reduce bacterial load in dentinal caries.
