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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Feasibility of Aorto-uni-iliac Endovascular Aortic Repair Using the Gore Excluder for Abdominal Aortic Aneurysm
Takumi Sugiura1,2, Akira Yokka1, Toru Yamamoto1
1Department of Radiology, Fukui Prefectural Hospital, Japan.
Insights
Aorto-uni-iliac endovascular aortic repair using the Gore Excluder is feasible for abdominal aortic aneurysms when standard devices are unavailable. This approach demonstrated technical success and acceptable mid-term durability in selected emergency cases.
Area of Science:
- Vascular Surgery
- Endovascular Interventions
- Aortic Aneurysm Repair
Background:
- Abdominal aortic aneurysms (AAAs) pose significant risks, necessitating effective repair strategies.
- Endovascular aortic repair (EVAR) offers a less invasive alternative to open surgery.
- Aorto-uni-iliac (AUI) configuration is an EVAR strategy used when standard bifurcated grafts are unsuitable.
Purpose of the Study:
- To assess the feasibility and mid-term durability of AUI endovascular aortic repair (EVAR) using the Gore Excluder device.
- To evaluate outcomes in patients where dedicated AUI devices were unavailable or unsuitable.
Main Methods:
- Retrospective review of five AUI EVAR cases for AAA using the Gore Excluder (January 2014-January 2024).
- Evaluation of technical success, overall survival, aneurysm sac changes, endoleaks, and secondary interventions.
- AUI configuration achieved via off-label use of aortic extenders or inverted contralateral legs.
Main Results:
- All five cases achieved technical success, including three emergency procedures.
- No aneurysm-related deaths occurred during a median follow-up of 35 months.
- Slight type III endoleaks resolved spontaneously; no sac enlargement observed, indicating acceptable durability.
Conclusions:
- AUI EVAR with the Gore Excluder is a feasible option for AAA when dedicated devices are unavailable or contraindicated.
- This technique provides acceptable mid-term durability, particularly in emergency settings.
- Off-label use of components can facilitate AUI EVAR in challenging cases.
Abstract:
Purpose: To evaluate the feasibility of aorto-uni-iliac endovascular aortic repair using the Gore Excluder in selected patients. Material and Methods: This retrospective study reviewed five cases of aorto-uni-iliac endovascular aortic repair for abdominal aortic aneurysm using the Gore Excluder between January 2014 and January 2024. Patient demographics, procedural details, and postoperative outcomes were evaluated. Study endpoints included technical success, overall survival, aneurysm sac changes, endoleak occurrence, secondary interventions, and aneurysm-related death to evaluate feasibility and mid-term durability. Technical success was defined as successful stent graft deployment without conversion to open repair. Results: The cohort included one elective case in which a dedicated aorto-uni-iliac device was deemed unsuitable, three cases converted intraoperatively from bifurcated to aorto-uni-iliac configuration, and one case in which the dedicated device was unavailable. The aorto-uni-iliac configuration was achieved through off-label use of aortic extenders or an upside-down contralateral leg. All cases were technically successful. Three cases were emergency procedures. All cases required femoro-femoral crossover bypass. Slight type III endoleaks were detected in two cases on completion aortography but had resolved on postoperative computed tomography on days 11 and 16, respectively. No type III endoleaks were observed in any case during follow-up. No aneurysm-related deaths occurred. Over a median follow-up of 35 months (range: 1-62; excluding one same-day death), no sac enlargement was observed, suggesting acceptable durability. Median overall survival was 1,100 days (range: 0-1,966). Conclusions: Aorto-uni-iliac endovascular aortic repair using the Gore Excluder for abdominal aortic aneurysm is feasible when dedicated aorto-uni-iliac devices are unavailable or unsuitable, particularly in emergencies.
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