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Updated: Jan 12, 2026

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Published on: January 22, 2022
Massive diaphragmectomy combined with pericardiectomy for ovarian cancer: a case report
Yuanyuan Guo1, Liang Chen1, Jianlei Wu1
1Department of Gynecological Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University & Shandong Academy of Medical Sciences, 440 Jiyan Road, Jinan 250117, PR China.
Introduction:
Ovarian cancer metastasis to the pericardium is rare. Surgical resection of such metastases is exceptionally uncommon, with only limited cases reported in the literature.
Case Report:
We report a case of platinum-sensitive recurrent ovarian cancer treated with surgical resection, including massive diaphragmectomy and pericardiectomy. The surgery involved removing an 8 cm diaphragmatic lesion and a 5 cm pericardial defect, which was intentionally enlarged to 7 cm to prevent incarceration. A patch repair was used for the large diaphragm defect. Postoperatively, the patient recovered well and subsequently underwent chemotherapy and targeted therapy without complications.
Conclusion:
Ovarian cancer metastasis to the central tendon of the diaphragm can involve the pericardium, requiring complex and high-risk surgery. Such cases necessitate a multidisciplinary approach led by a team of experienced gynecologic oncologists.

