Clinical and echocardiographic outcomes of combined CABG and MV repair

Rajat Sindwani1, Gurmeet Singh1, Harneet Singh Khurana2

  • 1Department of Cardiothoracic and Vascular Surgery, Hero Heart DMC Institute, Ludhiana, Punjab, India.

Bioinformation
|October 31, 2025
PubMed

Insights

Coronary Artery Bypass Grafting with mitral valve repair effectively treats moderate to severe mitral regurgitation, improving patient outcomes and eliminating residual regurgitation in most cases.

Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology
  • Cardiac Valve Repair

Background:

  • Moderate to severe mitral regurgitation (MR) often coexists with coronary artery disease (CAD).
  • Surgical intervention for both conditions requires careful patient selection and procedural planning.

Purpose of the Study:

  • To evaluate the outcomes of patients undergoing Coronary Artery Bypass Grafting (CABG) with concomitant mitral valve (MV) repair for moderate to severe MR.
  • To assess the efficacy and safety of this combined surgical approach in a high-comorbidity patient population.

Main Methods:

  • A mixed-method observational study design was employed.
  • Patients undergoing CABG with MV repair for moderate to severe MR were evaluated.
  • Data collected included patient demographics, comorbidities, and clinical outcomes at discharge and 12 months.

Main Results:

  • The study population predominantly consisted of males aged 61-70 years with high rates of Type 2 diabetes and triple-vessel CAD.
  • At discharge, 94.7% of patients improved to NYHA class II.
  • Residual MR was eliminated in 97.1% of patients by discharge, with sustained improvement at 12 months.

Conclusions:

  • CABG with concomitant MV repair is a viable and effective treatment option for patients with moderate to severe MR and concomitant CAD.
  • This combined surgical approach demonstrates significant improvement in functional status and successful elimination of MR, even in patients with substantial comorbidities.

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