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Investigating Intestinal Inflammation in DSS-induced Model of IBD
Published on: February 1, 2012
Comparative study of fecal calprotectin levels in ulcerative colitis versus irritable bowel syndrome
Geethika Sai Satyavasukiaparna Garaga1, Kalvakota Maninithya2, Nadampalli Deepica Rani3
1Department of Gastroenterology and Hepatology, Yashoda Hospitals, Hyderabad, Telangana, India.
Abstract:
Fecal calprotectin has been evaluated on its ability to differentiate between ulcerative colitis (UC) and irritable bowel syndrome (IBS). Hence, sixty patients were stratified according to clinical and histological characteristic as UC (Group A) and IBS (Group B). The levels of calprotectin in UC patients (623.5 0 g) were significantly higher than in IBS patients (36.4 0 g), (p < 0.001). The high presence was observed in 93.3 percent of UC subjects and only 6.7 percent of IBS subjects. Thus, fecal calprotectin works well in distinguishing UC and IBS, and facilitates the non-invasive diagnosis of UC.
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