Kuwait Heart Foundation Registry of Acute Coronary Events: Design and Rationale of Large Contemporary Registry of
Mohammad Zubaid1, Mousa Akbar2, Abdullah Alenezi3
1Department of Medicine, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.
Insights
The Kuwait Heart Foundation Registry of Acute Coronary Events (KHF RACEs) is a new registry for acute coronary syndromes (ACSs) in Kuwait. This study details its design, aiming to improve understanding of ACS patient care and outcomes in the region.
Area of Science:
- Cardiology
- Public Health
- Clinical Research
Background:
- Acute coronary syndromes (ACSs) represent a significant health burden globally.
- Limited contemporary data exists on ACS patient characteristics and management in the Middle East.
- Establishing large-scale registries is crucial for understanding disease patterns and improving patient care.
Purpose of the Study:
- To describe the design and rationale of the Kuwait Heart Foundation Registry of Acute Coronary Events (KHF RACEs).
- To establish a prospective, multicenter registry for patients diagnosed with ACS in Kuwait.
- To provide a foundation for future research on ACS management and outcomes in the region.
Main Methods:
- The KHF RACEs is a prospective, multicenter, observational cohort registry.
- It enrolled consecutive patients admitted with a working diagnosis of ACS across 8 hospitals in Kuwait.
- Data collected included demographics, risk factors, medical history, medications, examination findings, investigations, management, and in-hospital/30-day outcomes.
Main Results:
- The registry enrolled patients from May 15, 2023, involving 124 investigators.
- Data was prospectively collected via an online system.
- The registry captured comprehensive details on patient profiles, treatments, and immediate outcomes.
Conclusions:
- KHF RACEs is the largest contemporary ACS registry in the Middle East, demonstrating successful implementation of multicenter registries.
- Planned analyses will investigate guideline adherence, impact of demographics (age, gender, diabetes, insurance) on outcomes, and cardiac catheterization-related results.
- The registry is expected to provide valuable insights into ACS management and patient outcomes in Kuwait and the wider region.
Aim:
The aim of this study was to describe the design and rationale of a registry of patients with acute coronary syndromes (ACSs) in Kuwait.
Methods:
Kuwait Heart Foundation Registry of Acute Coronary Events (KHF RACEs) is a prospective, multicenter, observational, cohort-based registry of consecutive patients admitted to hospitals in Kuwait with a working diagnosis of ACSs. The trial is registered at "Clinical Trials.gov" number NCT05857735 and enrollment started on May 15, 2023. It involved 8 hospitals and 124 investigators. Data were collected prospectively and entered into an online system specifically created for this registry. This included demographic data, risk factors, past medical history, medications at admission and discharge, pertinent findings on physical examination at admission, inhospital investigations, and management including cardiac catheterization and subsequent percutaneous coronary interventions. The observed outcomes included inhospital and 30-day mortality and major adverse cardiac events.
Conclusion:
KHF RACE is the largest contemporary ACS registry in the Middle East. It provides an example of how large multicenter registries can be carried out successfully in this part of the world. Results are expected to shed light on the adherence to guidelines in our daily practice and its influence on patients' outcomes. Several analyses of the data are planned, including the influence of age, gender, diabetes, and insurance status on outcomes. Other planned analyses will be relating to cardiac catheterization and its related outcomes.
More Related Videos
10:38Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
Published on: January 16, 2019
13:07Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Related Concept Videos
01:30Coronary Artery Disease I: Introduction
01:30Acute Coronary Syndrome I: Introduction
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
01:30Acute Coronary Syndrome III: Diagnostic Studies
01:28Acute Coronary Syndrome IV: Interprofessional Care
01:26Acute Coronary Syndrome V: Nursing Management