Tunable NIR-II photoluminescence in peptidic gold nanoclusters via dynamic covalent polymerization
Furhan Abdul Rezak1,2, José García Coll3, Galina V Dubacheva2
1Institut pour l'Avancée des Biosciences (IAB), Université Grenoble Alpes, INSERM U1209, CNRS-UMR 5309, 38700, Grenoble, France. xavier.le-guevel@univ-grenoble-alpes.fr.
Abstract:
Tailoring the surface environment of gold nanoclusters is critical for enhancing their optical performance and expanding their applications in bioimaging, notably in the second near-infrared biological window. Here, we report hydrazide-rich peptide AuNCs featuring shell rigidification via dynamic covalent acylhydrazone formation with peptide bisaldehydes of varied hydrophobicity. This strategy restricts ligand motion, enhancing photoluminescence emission efficiency, and enables investigation of how the ligand shell hydrophobicity influences the optical properties of the nanoclusters.
More Related Videos
Related Concept Videos
IR Absorption Frequency: Hybridization
Among the sp, sp2, and sp3 hybridized orbitals, sp orbitals have the maximum s character (50%). Consequently, the electrons are held more closely to the nucleus, resulting in stronger and shorter C–H bonds that stretch at a...
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)


