Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

604
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
604
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

528
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
528
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

760
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
760
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

1.1K
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
1.1K
Cancer Prevention02:59

Cancer Prevention

7.6K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
7.6K
Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

725
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
725

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

NON-CELIAC GLUTEN/WHEAT SENSITIVITY (NCG/WS). A BRAZILIAN CASES SERIES.

Arquivos de gastroenterologia·2026
Same author

TRENDS IN THE CLINICALPRESENTATION OF CELIAC DISEASE IN BRAZILIAN ADULTS SEEN IN THE LAST 50 YEARS IN A PRIVATE OFFICE.

Arquivos de gastroenterologia·2026
Same author

Histopathological evaluation in post-mortem renal biopsies of patients with COVID-19 and comorbidities: a case-control study.

Sao Paulo medical journal = Revista paulista de medicina·2026
Same author

CLINICAL AND HISTOLOGICAL COMPARISON OF CELIAC DISEASE AND DERMATITIS HERPETIFORMIS IN MALE PATIENTS: A TEN-YEAR RETROSPECTIVE STUDY.

Arquivos de gastroenterologia·2025
Same author

TELEREGULATION IN GASTROENTEROLOGY AND THE BOTTLENECK OF SPECIALIZED HEALTH CARE.

Arquivos de gastroenterologia·2025
Same author

SKELETAL HEALTH ASSESSMENT IN BRAZILIAN MEN WITH CELIAC DISEASE AT DIAGNOSIS: HOW IMPORTANT IS IT?

Arquivos de gastroenterologia·2024

Related Experiment Video

Updated: Jan 12, 2026

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
03:05

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

1.5K

PREVALENCE OF GASTRIC CANCER AND PRENEOPLASTIC LESIONS: A CROSS-SECTIONAL STUDY IN A MEDIUM-RISK WESTERN POPULATION.

Victor Cangussu Teixeira Campos1, Mayara Pezzini Arantes2, Luiz Roberto Kotze2

  • 1Complexo Hospital de Clínicas da Universidade Federal do Paraná, Unidade de Endoscopia Digestiva, Curitiba, PR, Brasil.

Arquivos De Gastroenterologia
|October 31, 2025
PubMed
Summary

Gastric cancer precursor lesions were found in 25% of patients during routine endoscopies. Early detection of these lesions is crucial for developing effective gastric cancer prevention strategies.

More Related Videos

Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer
07:50

Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer

Published on: September 18, 2020

6.1K
Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
06:21

Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer

Published on: May 10, 2024

1.2K

Related Experiment Videos

Last Updated: Jan 12, 2026

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
03:05

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

1.5K
Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer
07:50

Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer

Published on: September 18, 2020

6.1K
Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
06:21

Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer

Published on: May 10, 2024

1.2K

Area of Science:

  • Gastroenterology
  • Oncology
  • Pathology

Background:

  • Late diagnosis of gastric cancer is often due to undetected precursor lesions.
  • Routine upper gastrointestinal endoscopy is a primary diagnostic tool.
  • Identifying precursor lesions is key to improving gastric cancer outcomes.

Purpose of the Study:

  • To determine the prevalence of gastric cancer and its precursor lesions.
  • To investigate these findings in patients undergoing routine endoscopy in Brazil.
  • To establish baseline data for prevention strategies.

Main Methods:

  • Retrospective cross-sectional study of 1,071 patients aged >40 years.
  • Exclusion of patients with multiple endoscopies, no biopsies, or specific pre-existing conditions.
  • Histopathological review and Operative Link on Gastritis Assessment (OLGA) classification for gastric mapping.

Main Results:

  • 25.9% of patients had malignant precursor lesions or cancer.
  • Significant correlations found between lesions and male sex, age >80, chronic atrophic gastritis, intestinal metaplasia, and H. pylori infection.
  • OLGA stages III and IV observed in 5.2% of patients undergoing gastric mapping.

Conclusions:

  • Up to 25% of patients exhibit gastric cancer precursor lesions, mostly low-risk.
  • Further prospective studies are needed to assess cancer risk in these individuals.
  • Data supports the need for targeted prevention strategies for gastric cancer.