Related Experiment Video

Updated: Jan 12, 2026

A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy
09:56

A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy

Published on: February 21, 2025

1.3K

Transdifferentiation From Multiple Myeloma to Myeloid Sarcoma in the Setting of CAR T-Cell Therapy

Diana Cirstea1, Kathleen Gallagher2, Maxx King2

  • 1Center for Multiple Myeloma, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

Clinical Lymphoma, Myeloma & Leukemia
|October 31, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
BCMACilta-celImmunotherapyPlasma neoplasmTransformation to leukemia

More Related Videos

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
12:16

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

15.4K
Manufacturing Chimeric Antigen Receptor CAR T Cells for Adoptive Immunotherapy
06:51

Manufacturing Chimeric Antigen Receptor CAR T Cells for Adoptive Immunotherapy

Published on: December 17, 2019

15.8K

Related Experiment Videos

Last Updated: Jan 12, 2026

A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy
09:56

A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy

Published on: February 21, 2025

1.3K
A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
12:16

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

15.4K
Manufacturing Chimeric Antigen Receptor CAR T Cells for Adoptive Immunotherapy
06:51

Manufacturing Chimeric Antigen Receptor CAR T Cells for Adoptive Immunotherapy

Published on: December 17, 2019

15.8K

Related Concept Videos

Differentiation of Common Myeloid Progenitor Cells01:15

Differentiation of Common Myeloid Progenitor Cells

3.9K
Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...
3.9K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.6K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.6K

Articles linked to this work by shared authors, journal, and citation graph.

Improved chlorination and rapid water quality assessment in response to an outbreak of acute watery diarrhea in Somali Region, Ethiopia.

Journal of water, sanitation, and hygiene for development : a journal of the International Water Association·2026

Gene regulatory elements determine efficacy of BCMA-targeted CAR-T cell products.

Journal for immunotherapy of cancer·2026

ASTCT Consensus Grading for Toxicities after Immune Effector Cell Therapy.

Transplantation and cellular therapy·2026

Rational Engineering of Notch1 Signaling to Boost the Proliferation of CD19-BBζ CAR-T.

Blood·2026

T-cell immunosenescence limits CD19 CAR T-cell function in chronic lymphocytic leukemia.

Blood·2026

Microfluidic T-Chip enables one-step clinical-scale T-cell purification from blood products for CAR T-cell manufacturing.

bioRxiv : the preprint server for biology·2026

Testicular Plasmacytoma: A 25-Year Experience From a High-Volume Tertiary Center and Comparative Review of the Literature.

Clinical lymphoma, myeloma & leukemia·2026

SOHO State of the Art Updates and Next Questions | The Role of Maintenance Therapy Following Autologous Stem Cell Transplantation for Newly Diagnosed Multiple Myeloma.

Clinical lymphoma, myeloma & leukemia·2026

Acute Leukemia During the First Six Months of Life: A Population-Based Analysis of Survival by Leukemia Type.

Clinical lymphoma, myeloma & leukemia·2026

Noninterchangeability of Serum-Free Light Chain Assays at IMWG Thresholds: Analysis of 2117 Paired Samples.

Clinical lymphoma, myeloma & leukemia·2026

The 21st International ``Ponte di Legno'' Childhood Acute Lymphoblastic Leukemia Workshop Report: Progress and Emerging Opportunities.

Clinical lymphoma, myeloma & leukemia·2026

Cutaneous Toxicities of T-Cell-Redirecting Therapies in Multiple Myeloma: An EADV Task Force Position Paper and Practical Recommendations.

Clinical lymphoma, myeloma & leukemia·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us