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Intranasal Insulin Administration for Reducing Postoperative Delirium After Hip Fracture Surgery in Elderly Patients

Fu-Shan Xue1, Yong-Bao Lin2, Dan-Feng Wang2

  • 1Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fuzhou, China; Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
|October 31, 2025
PubMed
Abstract

No abstract available in PubMed .

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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