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The Big BIT maize experiment: A large multi-location, multi-year, multi-tester, multi-population predictive breeding

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The Big Breeding Innovation Team (Big BIT) maize experiment validated genomic prediction for breeding. Early genetic evaluation using wide-area testing data optimizes maize inbred and variety development.

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Area of Science:

  • Plant genetics and breeding
  • Genomic prediction
  • Maize (Zea mays L.)

Background:

  • The Big Breeding Innovation Team (Big BIT) conducted a large-scale maize experiment to validate genomic data-informed predictive breeding.
  • The study involved multi-location, multi-year, multi-tester, and multi-population trials of F1 maize hybrids.

Purpose of the Study:

  • To describe the design and unique features of the Big BIT experiment.
  • To discuss practical learnings for optimizing predictive breeding strategies in maize.

Main Methods:

  • Utilized descriptive summary statistics on multi-year field data.
  • Performed large-scale cross-validations to assess predictive abilities.
  • Analyzed genomic estimated breeding values (GEBVs) for individuals and families.

Main Results:

  • Provided multi-year field data-based evidence for predictive breeding strategies.
  • Demonstrated the effectiveness of wide-area testing training datasets for early genetic evaluation.
  • Confirmed findings for selection candidates with and without phenotypic records.

Conclusions:

  • Early-stage genetic evaluation in maize improvement should leverage GEBVs from wide-area testing datasets.
  • This approach is effective for inbred and variety development.
  • The Big BIT experiment offers valuable insights for plant breeders aiming to optimize predictive breeding.