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Movement Disorders in West Nile Virus Infection: A Systematic Review of Reported Cases and Conference Abstracts
Ravindra Kumar Garg1, Shweta Pandey2, Sanjay Singhal3
1Department of Neurology, Era's Lucknow Medical College & Hospital, Era University, Lucknow, India.
Movement Disorders Clinical Practice
|November 1, 2025
Summary
West Nile virus infection can cause significant movement disorders, particularly opsoclonus myoclonus syndrome. Early recognition and understanding of these neurological complications are crucial for patient outcomes.
Area of Science:
- Neurology
- Infectious Diseases
- Neuroscience
Background:
- West Nile virus (WNV) is a major arbovirus causing neuroinvasive disease.
- While encephalitis and paralysis are known WNV complications, associated movement disorders are poorly understood.
- Existing evidence on WNV-induced movement disorders is fragmented.
Conclusions:
- Movement disorders, especially opsoclonus myoclonus syndrome, are under-recognized manifestations of WNV neuroinfection.
- Viral neurotropism and immune responses are implicated in the pathogenesis.
- Further research is needed to fully elucidate these neurological complications.
