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Response to Li and Wang: Slow Oscillations and Spatial Memory: Reflecting on the Limited Behavioral Effects of

Anna E Mullins1, Ankit Parekh1, Korey Kam1

  • 1David M. Rapoport Sleep Research Laboratory, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States.

Sleep
|November 1, 2025
PubMed
Abstract

No abstract available in PubMed .

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Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge: